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Product details

File Size: 2294 KB

Print Length: 334 pages

Publisher: St. Martin's Press; 1 edition (March 13, 2012)

Publication Date: March 13, 2012

Sold by: Macmillan

Language: English

ASIN: B0068ZTEE4

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Amazon Best Sellers Rank:

#180,983 Paid in Kindle Store (See Top 100 Paid in Kindle Store)

I started out as just another pre-medical freshman at Duke University in 1988, but I soon discovered that there was a prevailing mentality ruling mainstream science that was anathema to me, so I failed to thrive and maintain interest in the health sciences, bouncing around from one field to another within the sciences over the years.Most recently, after an aborted educational start in the field of natural medicine, I've come to the conclusion that -- aside from a much-needed nutritional revolution, the other half of what simply must happen in order to advance a TRUE health improvement revolution -- we simply must attack those intractable problems of human health for which dietary and nutritional changes simply would either not be reasonably sustainable, or at all sufficient.Much to the enraged chagrin of the Rockefellerian petro-pharmaceutical mafia that has ruled human health since the very late 1800's, we must find a way to actually repair maladaptive genes themselves and finally break the shackles of undue drug dependency once and for all.With all that said, I was delighted to find Ricki Lewis' book. She, perhaps alone, truly gets it. She truly understands that the nature of the problem is, as she so rightly puts it, "science for science's sake", rather than for the sake of the greater human race who sincerely needs what would otherwise be its civilizing fruits. Dr. Lewis has written a book that, to my knowledge, is singular of kind: it really gives a damn about the good, and shows us clearly and plainly how we may not only get there, but how we have already begun to get there -- to lasting and humane fixes rather than deliberately temporary and purely profiteering temporary band-aids.

As a disclaimer I should say that genetics is part of what I do at work, even though I don't work on gene therapy in particular. But aside from the topic, which I knew I would enjoy, I loved Dr. Lewis's writing and the way she effortlessly folded all the science (and the history of science) into the narrative. I am grateful to Dr. Lewis because through this wonderful book she humanized scientific research, giving a voice to the struggle of many patients and their families. She gave a voice and face to the doctors and the researchers who face many failures for every small step forward. Science is not dry and impersonal. Science is made of people, not just the scientists, but also the people who ultimately benefit from it, and the ones who, due to unfortunate events, didn't benefit but were still part of what made the successes possible. A wonderful read and a truly touching story.

I have been trained as a scientist and found this book to be fascinating. I remember taking a course in bioethics and learning of its renewed importance in the age of gene therapy. Unfortunately, the author chooses to concentrate on one case which she identifies as being true gene therapy when in fact, it is a partial treatment and may only be successful in a very small subset of young patients. The explanations of the genetics involved and the biological mechanisms used are primarily a means of showing off the author's talents. Having written a textbook for undergraduate students, I am sure she is knowledgeable but this should not be read as a textbook, but as a biographical description of what can go wrong and what can go right when gene therapy is attempted. Nevertheless, it does hold the reader's attention and that is no small thing when explicating such a difficult subject.

The topic of gene therapy is very interesting and worth reading, however this book tends to drag at times. There are many chapters that sporadically go over so many different patient's stories that it's difficult to remember the specifics of each patient or to care about so many stories. I felt this book would have been much more successful had it been more concise and was not so concerned with explaining every instance of gene therapy. Not a bad book, but in terms of writing was nothing of note.

The Forever Fix is a great read. Ricki Lewis delivers the history of gene therapy and tells the incredible story of Corey Haas in a way that is smart and engaging. The author makes the technical process easy to understand, even for those of us who are not scientists.The Forever Fix delves into other stories of gene therapy--including the epic failure that was the Jesse Gelsinger case--and provides a comprehensive view of how far the technology has come in the past few decades. This would have been an ideal book to read in some of my undergrad biotech/ human genetics courses. Given the multiple distractions of the Text Messaging/ Facebook era that we live in today, Ricki's approach of jumping from story to explanation, from anecdote to story, is refreshing and keeps readers engaged.I currently work in the biopharma industry and would also recommend this book to professionals looking to ramp up on gene therapy, as this is surely not the last we will hear of the groundbreaking technology.

I don't remember how I came across this book, but I am glad I did. As a biology teacher, I'm always looking for books to recommend to my students, and this one does not disappoint. Ricki Lewis takes you through the good, bad and ugly history of gene therapy by telling the stories of the individuals who have been treated for various inherited diseases using this technology.Lewis is a fantastic storyteller and teacher, making the very technical aspects of the biology involved easy to understand for laypeople. I plan on using parts of this book during the genetics unit that I teach later this semester, and assigning it as a book for my students to read next year.Even if you're not a biology lover, this book will definitely pique your interest.

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